Back to Search Start Over

A discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy

Authors :
Guocan Yu
Shan Yu
Manik Lal Saha
Jiong Zhou
Timothy R. Cook
Bryant C. Yung
Jin Chen
Zhengwei Mao
Fuwu Zhang
Zijian Zhou
Yijing Liu
Li Shao
Sheng Wang
Changyou Gao
Feihe Huang
Peter J. Stang
Xiaoyuan Chen
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

It is challenging to design photosensitizers (PS) with high quantum yields generating singlet oxygen due to severe aggregation between the hydrophobic PSs. Here they develop organoplatinum(II) metallatocage-based PS to overcome these challenges and show excellent antitumor effect.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.8199cec7a8594322a3448b9ce1685a6b
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-06574-7