Research progress of refeeding syndrome in patients with severe acute pancreatitis (重症急性胰腺炎患者再喂养综合征的研究进展)

Refeeding syndrome is a serious complication of malnutrition that occurs when someone who has been starved begins feeding again. Due to the lack of specificity, it is difficult to distinguish and the incidence is relatively high. Patients with severe acute pancreatitis are vulnerable to refeeding syndrome as high level of metabolism caused by serious condition or infection. Current researches mainly focus on pathogenesis, risk factors, prevention and nursing care of the refeeding syndrome. Because of the complexity and variation of clinical manifestations and weak specificity, the clinical practice of patients with refeeding syndrome is still controversial. This paper reviews studies on concept, current research status, pathogenesis, risk factors and other issues of refeeding syndrome in patients with severe acute pancreatitis, and puts forward suggestions for clinical practice, in order to provide reference for clinical diagnosis, prevention and treatment of refeeding syndrome. (再喂养综合征(RFS)是长期营养不良患者重新摄入营养初期机体代谢异常所导致的一系列代谢紊乱症候群, 由于缺乏特异性, 不易辨别, 发生率较高。重症急性胰腺炎患者因病情危重、感染等原因, 机体处于高分解、高代谢状态, 发生RFS风险较高。目前国内外关于RFS的研究, 涉及发病机制、危险因素、预防及护理等多方面, 但由于RFS的临床症状复杂多样且缺乏特异性, 易被临床医护人员忽视, 且具体护理措施仍然存在争议。本文通过对再喂养综合征定义、国内外现状、发生机制、危险因素等进行综述, 并提出护理建议, 以期为医护人员观察、识别和预防RFS提供参考依据。)