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Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus

Authors :
Angel Rivera-Calzada
Raquel Arribas-Bosacoma
Alba Ruiz-Ramos
Paloma Escudero-Bravo
Jasminka Boskovic
Rafael Fernandez-Leiro
Antony W. Oliver
Laurence H. Pearl
Oscar Llorca
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Vaccinia virus expresses two proteins that interfere with the host immune response. Here, authors provide the structural basis for this viral defence mechanism, conserved in other poxviruses such as the causatives agents of smallpox and monkeypox.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.8166a1fa6c9d47a0afe20872a86f6ed5
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-34843-z