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Aspects of the granulomatous reaction in the liver of mice infected and reinfected with two different geographical strains of Schistosoma mansoni

Authors :
Pedro Raso
Paulo Marcos Z. Coelho
Nivaldo H. Toppa
Rômulo T. Mello
Source :
Revista da Sociedade Brasileira de Medicina Tropical, Vol 27, Iss 4, Pp 221-226 (1994)
Publication Year :
1994
Publisher :
Sociedade Brasileira de Medicina Tropical (SBMT), 1994.

Abstract

In this study, which was undertaken in relation to the histopathologic behavior of two different strains (LE-Belo Horizonte, MG and SJ - São José dos Campos, SP) in infections and reinfections (homologous or heterologous) with Schistosoma mansoni, the authors confirmed a more accentuated pathogenicity of the SJ strain. All the reinfections showed the presence of typical granulomas of the acute phase, when performed either with the same strain (homologous) or with a different strain (heterologous) of the parasite of the primo infection. The possible mechanisms responsible for reactivation of the immunopathologic response in reinfections are discussed.

Details

Language :
English
ISSN :
16789849 and 00378682
Volume :
27
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Revista da Sociedade Brasileira de Medicina Tropical
Publication Type :
Academic Journal
Accession number :
edsdoj.80b59d7394e23aabdbe7924e93b39
Document Type :
article
Full Text :
https://doi.org/10.1590/S0037-86821994000400004