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intansv: an R package for integrative analysis of structural variations

Authors :
Lihua Jia
Na Liu
Fangfang Huang
Zhengfu Zhou
Xin He
Haoran Li
Zhizhan Wang
Wen Yao
Source :
PeerJ, Vol 8, p e8867 (2020)
Publication Year :
2020
Publisher :
PeerJ Inc., 2020.

Abstract

Identification of structural variations between individuals is very important for the understanding of phenotype variations and diseases. Despite the existence of dozens of programs for prediction of structural variations, none of them is the golden standard in this field and the results of multiple programs were usually integrated to get more reliable predictions. Annotation and visualization of structural variations are important for the understanding of their functions. However, no program provides these functions currently as far as we are concerned. We report an R package, intansv, which can integrate the predictions of multiple programs as well as annotate and visualize structural variations. The source code and the help manual of intansv is freely available at https://github.com/venyao/intansv and http://www.bioconductor.org/packages/devel/bioc/html/intansv.html.

Details

Language :
English
ISSN :
21678359
Volume :
8
Database :
Directory of Open Access Journals
Journal :
PeerJ
Publication Type :
Academic Journal
Accession number :
edsdoj.803fd4f4f7149e9b3e2e85a01178eb1
Document Type :
article
Full Text :
https://doi.org/10.7717/peerj.8867