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Serm Immuno Fixation Electrophoresis as a Diagnostic Method for Monoclonal Gammopathies in Patients with Multiple Myeloma

Authors :
Araz Muhammad Yousif
Nashwan Sleman Ablhad
Parween Abdulsamad Ismail
Source :
Al-Mustansiriyah Journal of Science, Vol 29, Iss 4, Pp 43-49 (2019)
Publication Year :
2019
Publisher :
Mustansiriyah University, 2019.

Abstract

B cells clonal expansion (producing abnormal amounts of immunoglobulins) reflect conditions causes a group of disorders called monoclonal gammopathies. They may be appearing as a range of diseases that consist of multiple myelomas (MM). The aim of this research is to use quantify and identify monoclonal gammopathy by serum immunofixation electrophoresis (SIFE) beside the serum protein electrophoresis (SPEP) assay as a tumor marker in the diagnosis of suspected multiple myeloma cases. Serum samples were collected from 94 patients with MM, and 30 persons as control, SPEP and SIFE were used for both groups. M band determined and evaluated of M protein by the Hellabio instruments. The results of this study showed significant elevation (p

Details

Language :
English
ISSN :
1814635X and 25213520
Volume :
29
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Al-Mustansiriyah Journal of Science
Publication Type :
Academic Journal
Accession number :
edsdoj.7fc44182aa542629b0ce60a7476c468
Document Type :
article
Full Text :
https://doi.org/10.23851/mjs.v29i4.461