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Dynamic aspects of ventricular interaction during exercise in HFpEF and in pre‐capillary pulmonary hypertension

Authors :
Mathias Claeys
Thibault Petit
Jan Bogaert
Andre La Gerche
Jan Los
Marion Delcroix
Rik Willems
Guido Claessen
Piet Claus
Source :
ESC Heart Failure, Vol 10, Iss 1, Pp 650-660 (2023)
Publication Year :
2023
Publisher :
Wiley, 2023.

Abstract

Abstract Aims The contribution of adverse ventricular interdependence remains undervalued in heart failure or pulmonary vascular disease, and not much is known about its dynamic nature during exercise and respiration. In this study, we evaluated ventricular interaction during exercise in patients with heart failure with preserved ejection fraction (HFpEF) and patients with chronic thromboembolic pulmonary hypertension (CTEPH) as compared with healthy controls. Methods and results Forty‐six subjects (10 controls, 19 CTEPH patients, and 17 HFpEF patients) underwent cardiac magnetic resonance imaging during exercise. Ventricular interaction was determined through analysis of the septal curvature (SC) of a mid‐ventricular short‐axis slice at end‐diastole, end‐systole, and early‐diastole, both in expiration and inspiration. Exercise amplified ventricular interaction in CTEPH patients and to a lesser extent in HFpEF patients (P

Details

Language :
English
ISSN :
20555822
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
ESC Heart Failure
Publication Type :
Academic Journal
Accession number :
edsdoj.7ea4b26654df4b93a313ee9543a476be
Document Type :
article
Full Text :
https://doi.org/10.1002/ehf2.14216