Comparison of the changes in the factors associated with the renal prognosis of non-elderly and elderly subjects treated with empagliflozin- a retrospective observation study in Japanese patients with type 2 diabetes

Hiroyuki Ito1, Suzuko Matsumoto1, Takuma Izutsu1, Eiji Kusano1, Shinya Nishio1, Shinichi Antoku1, Tomoko Yamasaki1, Toshiko Mori1, Michiko Togane1, Shigenori Ando2, Emiko Tsugami2 1Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital, Tokyo, Japan; 2Department of Pharmacy, Edogawa Hospital, Tokyo, JapanCorrespondence: Hiroyuki ItoDepartment of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital, 2-24-18, Higashikoiwa, Edogawa-ku, Tokyo 133-0052, JapanTel +81 3 3673 1221Fax +81 3 3673 1229Email ito@edogawa.or.jpPurpose: The factors associated with the renal prognosis over six months after the initiation of empagliflozin were compared between the non-elderly and elderly Japanese patients with type 2 diabetes.Patients and methods: In total, 132 patients treated with empagliflozin (10 mg, once daily) were studied as the safety analysis set. One hundred ten subjects whose medications were not changed during the observation period were investigated as the full analysis set to assess the effectiveness. The subjects were divided into two groups: non-elderly subjects (n=72) of