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A clinical case of disseminated BCG infection with a fatal outcome

Authors :
S. M. Kharit
Yu. E. Konstantinova
V. E. Karev
I. A. Karabak
A. I. Konev
K. K. Tikhomirova
M. E. Lozovskaja
Source :
Журнал инфектологии, Vol 16, Iss 1, Pp 94-103 (2024)
Publication Year :
2024
Publisher :
Journal Infectology, 2024.

Abstract

Complications after the introduction of the tuberculosis vaccine develop extremely rarely. They become accidentally vaccinated infants with undiagnosed severe immunodeficiency. The article considers a clinical case of the course of disseminated BCG infection with multiple organ damage in congenital immunodeficiency in a 9-month-old boy. The disease manifested itself acutely, the child’s condition worsened within a week, and its outcome was the death of the baby. Primary immunodeficiency was confirmed by the results of a pathoanatomic examination. The discussion provides a classification of complications after the introduction of BCG vaccine, the algorithm of the doctor’s actions in case of a suspected complication after vaccination, and also describes the main signs of immunodeficiency.

Details

Language :
Russian
ISSN :
20726732
Volume :
16
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Журнал инфектологии
Publication Type :
Academic Journal
Accession number :
edsdoj.7deff4404f0845aebc561cf48c98fa04
Document Type :
article
Full Text :
https://doi.org/10.22625/2072-6732-2024-16-1-94-103