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Case report: A case of giant malignant solitary fibrous tumor of the pleura with Doege-Potter’s syndrome and review of the literature

Authors :
Jie Li
Hong-Tao Tang
Qing Liu
Cai-Han Li
Wei-Yang Chen
Zeng-Wei Yu
Lei Wang
Lin Lin
Jin-Lan Zhao
Chun-Yan Zhao
Long-Qi Chen
Dong Tian
Source :
Frontiers in Oncology, Vol 14 (2024)
Publication Year :
2024
Publisher :
Frontiers Media S.A., 2024.

Abstract

The solitary fibrous tumor of the pleura (SFTP) is a rare intrathoracic neoplasm that commonly originates from the subpleural mesenchymal cells of the visceral pleura and accounts for less than 5% of all pleural tumors. We reported a case of a 54-year-old man with a two-week history of hypoglycemia, a six-month history of productive cough and fatigue, and chronic right chest pain. Radiological techniques revealed a giant intra-thoracic mass with hypervascularization, and pathological staining was carried out to make a definitive diagnosis of SFTP. Interventional embolization was conducted to block the main feeding vessels before the surgery, and an anterolateral thoracotomy combined with a transverse sternotomy was performed to achieve a complete resection, which demonstrates significant potential for further application in patients with unilateral giant SFTP. The postoperative course was uneventful, with no signs of hypoglycemia observed during the follow-up. Additionally, we reviewed and prospected the research progress on SFTP. The aim of this study is to enhance clinicians’ understanding of SFTP through our case and to provide a detailed review of the current research.

Details

Language :
English
ISSN :
2234943X
Volume :
14
Database :
Directory of Open Access Journals
Journal :
Frontiers in Oncology
Publication Type :
Academic Journal
Accession number :
edsdoj.7c92a380fa3a42c987a9449d78c349c3
Document Type :
article
Full Text :
https://doi.org/10.3389/fonc.2024.1437535