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Spatially non-uniform condensates emerge from dynamically arrested phase separation

Authors :
Nadia A. Erkamp
Tomas Sneideris
Hannes Ausserwöger
Daoyuan Qian
Seema Qamar
Jonathon Nixon-Abell
Peter St George-Hyslop
Jeremy D. Schmit
David A. Weitz
Tuomas P. J. Knowles
Source :
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Publication Year :
2023
Publisher :
Nature Portfolio, 2023.

Abstract

Biomolecular condensates with internal structure allow cells to further organise their processes. In this work the authors investigate how condensates can obtain an internal structure with droplets of dilute phase inside via kinetic, rather than purely thermodynamic driving forces.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.7c07f116ca21498c96519569ce628d42
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-023-36059-1