1223 Non-viral targeted knock-in of a KRAS G12D specific TCR, CD8αβ, and chimeric cytokine receptor in the TRAC locus outperforms lentiviral-based engineering of T cells

Authors :: Philip D Greenberg
Christopher A Klebanoff
Kim Nguyen
Gary Shapiro
Joshua Francis
Cheryl Black
Anthony Thomas
Meghan D Storlie
Allison P Drain
Nicholas Rouillard
Nathaniel Swanson
Santosh Narayan
Tyler Warner
Nicole Danek
Ken Gareau
James Parsons
Jinsheng Liang
Luhua Shen
Tanya Tetrault
Vince Nguyen
Iqraa Priyata
Sarah Vidyasagar
Xingyue He
Patrick J Browne
Rebecca C Lamothe
Gregory J Cost
Thomas M Schmitt
Smita S Chandran
Ankit Gupta
Damien Hallet
Loic Vincent
Source :: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Publication Year :: 2023
Publisher :: BMJ Publishing Group, 2023.

Subjects :: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282

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