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Enteral Nutrition Safety and Outcomes of Patients with COVID-19 on Continuous Infusion of Neuromuscular Blockers: A Retrospective Study
- Source :
- Journal of Nutrition and Metabolism, Vol 2023 (2023)
- Publication Year :
- 2023
- Publisher :
- Wiley, 2023.
-
Abstract
- Background. Intravenous infusions of neuromuscular blocking agents (NMBAs) and prone positioning are recommended for acute respiratory distress syndrome (ARDS) due to COVID-19. The safety of enteral nutrition (EN) during these treatments is unclear. This study assessed EN tolerance and safety during NMBA infusion in proned and nonproned patients with ARDS due to COVID-19. Methods. This retrospective study evaluated patients who were admitted to a tertiary-care ICU between March and December 2020, had ARDS due to COVID-19, and received NMBA infusion. We assessed their EN data, gastrointestinal events, and clinical outcomes. The primary outcome was gastrointestinal intolerance, defined as a gastric residual volume (GRV) ≥500 ml or 200–500 ml with vomiting. We compared proned and nonproned patients. Results. We studied 181 patients (mean age 61.2 ± 13.7 years, males 71.1%, and median body mass index 31.4 kg/m2). Most (63.5%) patients were proned, and 94.3% received EN in the first 48 hours of NMBA infusion at a median dose
- Subjects :
- Nutritional diseases. Deficiency diseases
RC620-627
Subjects
Details
- Language :
- English
- ISSN :
- 20900732
- Volume :
- 2023
- Database :
- Directory of Open Access Journals
- Journal :
- Journal of Nutrition and Metabolism
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.7b8a07abba674ff0a3532c688abf81f3
- Document Type :
- article
- Full Text :
- https://doi.org/10.1155/2023/8566204