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Regulation of erythroid differentiation in K562 cells by the EPAS1-IRS2 axis under hypoxic conditions

Authors :
Zhan Gao
Zhicai Li
Xiaowei Li
Jun Xiao
Cuiying Li
Source :
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Publication Year :
2023
Publisher :
Frontiers Media S.A., 2023.

Abstract

Red blood cells (RBCs) produced in vitro have the potential to alleviate the worldwide demand for blood transfusion. Hematopoietic cell differentiation and proliferation are triggered by numerous cellular physiological processes, including low oxygen concentration (

Details

Language :
English
ISSN :
2296634X
Volume :
11
Database :
Directory of Open Access Journals
Journal :
Frontiers in Cell and Developmental Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.7b87cca23764c3cb06bdd866817840a
Document Type :
article
Full Text :
https://doi.org/10.3389/fcell.2023.1161541