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Impact of horizontal gene transfer on emergence and stability of cooperative virulence in Salmonella Typhimurium

Authors :
Erik Bakkeren
Ersin Gül
Jana S. Huisman
Yves Steiger
Andrea Rocker
Wolf-Dietrich Hardt
Médéric Diard
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Salmonella Typhimurium virulence is costly and can be lost by mutation during infection. Bakkeren et al. show that virulence restoration via horizontal gene transfer is only transient while transmission bottlenecks promote long-term virulence stability.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.7b66723394194a4a9f2d07cb988f88cc
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-29597-7