Back to Search Start Over

Effect of partially hydrolyzed synbiotic formula milk on weight gain of late preterm and term infants—a multicenter study

Authors :
Suzan Sahin
Mehmet Buyuktiryaki
Nilufer Okur
Abdullah Baris Akcan
Mehmet Fatih Deveci
Sadik Yurttutan
Sezgin Gunes
Ayse Anik
Ramazan Ozdemir
Ozgun Uygur
Mehmet Yekta Oncel
Source :
Frontiers in Pediatrics, Vol 11 (2023)
Publication Year :
2023
Publisher :
Frontiers Media S.A., 2023.

Abstract

IntroductionData on the effectiveness of hydrolyzed infant formula containing both pre- and probiotics (synbiotic formula) on the growth of infants is still scarce. This retrospective study was designed to evaluate the effect of a partially hydrolyzed synbiotic formula on growth parameters and the possible occurrence of major gastrointestinal adverse events or morbidities in infants born via cesarean section (C-section) delivery.MethodsC-section-delivered term and late preterm infants who received either partially hydrolyzed synbiotic formula, standard formula, or maternal milk and followed at seven different hospitals from five different regions of Turkey, during a 1-year period with a minimum follow-up duration of 3 months were evaluated retrospectively. All the included infants were evaluated for their growth patterns and any kind of morbidity such as diarrhea, constipation, vomiting, infection, or history of hospitalization.ResultsA total of 198 infants (73 in the human milk group, 61 in the standard formula group, and 64 in the partially hydrolyzed synbiotic formula group) reached the final analysis. The groups were similar regarding their demographic and perinatal characteristics. No difference was observed between the three groups regarding gastrointestinal major side effects. Growth velocities of the infants in the human milk and partially hydrolyzed synbiotic formula groups during the first month of life were similar whereas the weight gain of infants in the standard formula group was significantly less than these two groups (p

Details

Language :
English
ISSN :
22962360
Volume :
11
Database :
Directory of Open Access Journals
Journal :
Frontiers in Pediatrics
Publication Type :
Academic Journal
Accession number :
edsdoj.7b3a92ddfe0146419fe2c5bb84b5d06b
Document Type :
article
Full Text :
https://doi.org/10.3389/fped.2023.1270442