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Protector effect of Helianthus annuus (Sunflower) on myocardial infarction in New Zealand rabbit

Authors :
Edith Guardia-Espinoza
Gianina Liseth del Carmen Herrera-Hurtado
Saúl Garrido-Jacobi
Danitza Cárdenas-Peralta
Christian Martínez-Romero
Pedro Hernández-Figueroa
Mary Condori-Calizaya
Juan La Barrera-Llacchua
Miguel Flores-Ángeles
Source :
Revista Peruana de Medicina Experimental y Salud Pública, Vol 32, Iss 1, Pp 80-86 (2015)
Publication Year :
2015
Publisher :
Instituto Nacional de Salud, 2015.

Abstract

Objectives. Determine the protective effect of oil Helianthus annuus (Sunflower) on myocardial infarction induced by epinephrine in New Zealand rabbits. Materials and methods. The rabbits were randomized into five groups (8 per group): blank, negative control, experimental 1 (10 mg / kg), experimental 2 (20 mg / kg) and three experimental (40 mg/ kg). Experimental groups 1, 2 and 3 received Helianthus annuus oil for two weeks. Epinephrine (2 mg/Kg) to the negative, Experimental Control 1, 2 and 3 groups was given over two consecutive days with an interval of 24 h after pretreatment with oil. Twenty four hours after the last administration, the rabbits were anesthetized and sacrificed. Serum troponin I and polymorphonuclear evaluated by .mu.m.sup.2. Results. Significant difference between the negative control group and the experimental groups 1, 2 and 3 was found in the serum variables troponin I and polymorphonuclear by .mu.m.sup.2. Conclusions. Helianthus annuus oil at doses of 20 mg/kg has protective effect on myocardial infarction induced by epinephrine in New Zealand rabbits.

Details

Language :
Spanish; Castilian
ISSN :
17264634 and 17264642
Volume :
32
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Revista Peruana de Medicina Experimental y Salud Pública
Publication Type :
Academic Journal
Accession number :
edsdoj.7aae9be511ca4e129ea45d0dfd52011e
Document Type :
article
Full Text :
https://doi.org/10.17843/rpmesp.2015.321.1578