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Joint morphogenetic cells in the adult mammalian synovium

Authors :
Anke J. Roelofs
Janja Zupan
Anna H. K. Riemen
Karolina Kania
Sharon Ansboro
Nathan White
Susan M. Clark
Cosimo De Bari
Source :
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Publication Year :
2017
Publisher :
Nature Portfolio, 2017.

Abstract

The stem cells that maintain and repair adult joint tissues in mammals, including articular cartilage, remain incompletely defined. Here the authors perform lineage tracing studies in adult mice and find an ontogenetically defined progenitor cell population that is functional in the synovial joint and distinct from previously reported mesenchymal stem cell populations.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
8
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.7aa1bdfe37f5443580838119bffe69ec
Document Type :
article
Full Text :
https://doi.org/10.1038/ncomms15040