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Diagnostic accuracy of BASIC-Q for detection of cognitive impairment in a primary care setting – a cross-validation study

Authors :
Anne-Britt Oxbøll
Kasper Jørgensen
T. Rune Nielsen
Sofie D. Christiansen
Ann Nielsen
Frans B. Waldorff
Gunhild Waldemar
Source :
BMC Geriatrics, Vol 24, Iss 1, Pp 1-11 (2024)
Publication Year :
2024
Publisher :
BMC, 2024.

Abstract

Abstract Objectives This study aims to evaluate the diagnostic accuracy and reliability of a new, brief questionnaire, ‘Brief Assessment of Impaired Cognition– Questionnaire’ (BASIC-Q) for detection of cognitive impairment, primarily developed for use in primary care. BASIC-Q has three components: Self-report, Informant report, and Orientation. Self-report and Orientation are completed by the individual and Informant report is answered by a close relative. Methods We included 275 participants ≥ 70 years, without a prior diagnosis of dementia, and with a close relative who agreed to participate as an informant. Participants were included prospectively in 14 general practices in urban and rural Denmark using a convenience sampling method. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), the informant-completed Functional Activities Questionnaire (FAQ) and reported memory concern were used as a reference standard for the classification of the participants’ cognitive function. Results BASIC-Q demonstrated a fair to good diagnostic accuracy to differentiate between people with cognitive impairment and normal cognition with an area under the ROC curve (AUC) of 0.84 (95% CI 0.79–0.89) and a sensitivity and specificity of 0.80 (95% CI 0.72–0.87) and 0.71 (95% CI 0.63–0.78). A prorated BASIC-Q score derived from BASIC-Q without Informant report had significantly lower classification accuracy than the full BASIC-Q. The test-retest reliability of BASIC-Q was good with an intraclass correlation coefficient of 0.84. Conclusion BASIC-Q is a brief, easy-to-use questionnaire for identification of cognitive impairment in older adults. It demonstrated fair to good classification accuracy in a general practice setting and can be a useful case-finding tool when suspecting dementia in primary health care.

Details

Language :
English
ISSN :
14712318
Volume :
24
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Geriatrics
Publication Type :
Academic Journal
Accession number :
edsdoj.7a76872c231941069d20767e926e1b46
Document Type :
article
Full Text :
https://doi.org/10.1186/s12877-024-04675-1