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Magneto-responsive Cell Culture Substrates that can be Modulated in situ
- Source :
- CHIMIA, Vol 73, Iss 1-2 (2019)
- Publication Year :
- 2019
- Publisher :
- Swiss Chemical Society, 2019.
-
Abstract
- Abstract: Understanding the interaction between cells and their environment is fundamental for mechanobiology. To mimic the behavior of cells in physiological and pathological conditions, synthetic substrates must have topographical and/or mechanical properties that evolve in time. Dynamic substrates mainly rely on stimuli-responsive materials where an external stimulus induces controlled variations in topography or mechanics. Herein, we describe the development of a dynamic cell culture substrate where mechanical properties are reversibly tuned in situ using magnetically-responsive superparamagnetic iron oxide nanoparticles (SPIONs).
Details
- Language :
- German, English, French
- ISSN :
- 00094293 and 26732424
- Volume :
- 73
- Issue :
- 1-2
- Database :
- Directory of Open Access Journals
- Journal :
- CHIMIA
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.7a69cbd3054742169199c0f6641882c0
- Document Type :
- article
- Full Text :
- https://doi.org/10.2533/chimia.2019.51