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Targeting aberrant replication and DNA repair events for treating breast cancers

Authors :
Subapriya Rajamanickam
Jun Hyoung Park
Panneerdoss Subbarayalu
Santosh Timilsina
Kaitlyn Bates
Pooja Yadav
Saif S. R. Nirzhor
Vijay Eedunuri
Tabrez A. Mohammad
Kwang Hwa Jung
Benjamin Onyeagucha
Nourhan Abdelfattah
Raymond Benevides
Grace Lee
Yidong Chen
Ratna Vadlamudi
Andrew Brenner
Virginia Kaklamani
Ismail Jatoi
John Kuhn
Robert Hromas
Yogesh K. Gupta
Benny A. Kaipparettu
Jack L. Arbiser
Manjeet K. Rao
Source :
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

A report of the small molecule Carbazole Blue demonstrates inhibition of breast cancer growth and metastasis without adverse effects on normal tissue.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
5
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.7a4cae1b109747c5bf6ef01173eb2df8
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-022-03413-w