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A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion
- Source :
- Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
- Publication Year :
- 2018
- Publisher :
- Nature Portfolio, 2018.
-
Abstract
- Catabolizing lignin-derived aromatic compounds requires an aryl-O-demethylation step. Here the authors present the structures of GcoA and GcoB, a cytochrome P450-reductase pair that catalyzes aryl-O-demethylations and show that GcoA displays broad substrate specificity, which is of interest for biotechnology applications.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 9
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.794b35c1169a406b89565b7b8ae40208
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-018-04878-2