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The Relationship between the Serum Aspartate Aminotransferase/Alanine Aminotransferase Ratio and Pulse Pressure in Korean Adults with Hypertension
- Source :
- Korean Journal of Clinical Laboratory Science, Vol 53, Iss 3, Pp 241-248 (2021)
- Publication Year :
- 2021
- Publisher :
- The Korean Society for Clinical Laboratory Science, 2021.
-
Abstract
- The present study was conducted to assess the relationship between aspartate aminotransferase/ alanine aminotransferase (AST/ALT) ratio and pulse pressure in Korean adults with hypertension. Data from 1,515 adults from the sixth Korean National Health and Nutrition Examination Survey (KNHANES VI–3, 2015) were analyzed. There were several key findings in the present study. First, aspartate aminotransferase (odds ratio [OR], 1.018; 95% confidence interval [CI], 1.002 to 1.033), alanine aminotransferase (OR, 0.982; 95% CI, 0.969 to 0.996), and aspartate aminotransferase/ alanine aminotransferase ratio (OR, 1.367; 95% CI, 1.027 to 1.819) were the independent factors determining high pulse pressure. Second, after adjusting for related variables [age, gender, smoking, alcohol consumption, regular exercise, total cholesterol (TC), triglycerides (TGs), high-density lipoprotein-cholesterol (HDL-C), fasting plasma glucose (FPG), body mass index (BMI), and waist circumference (WC)], the ORs of high pulse pressure with the 1st quartile as a reference were significantly higher in the 4th quartile of aspartate aminotransferase/alanine aminotransferase ratio [1.632 (95% CI, 1.113∼2.393)]. The high pulse pressure was positively associated with aspartate aminotransferase and alanine aminotransferase/alanine aminotransferase ratio in Korean adults with hypertension, but was inversely associated with alanine aminotransferase.
- Subjects :
- ast/alt ratio
hypertension
pulse pressure
Medicine (General)
R5-920
Subjects
Details
- Language :
- English, Korean
- ISSN :
- 17383544 and 22881662
- Volume :
- 53
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Korean Journal of Clinical Laboratory Science
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.7923b33ab709470ea98f971e13ed1388
- Document Type :
- article
- Full Text :
- https://doi.org/10.15324/kjcls.2021.53.3.241