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Development of a chimeric Zika vaccine using a licensed live-attenuated flavivirus vaccine as backbone
- Source :
- Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
- Publication Year :
- 2018
- Publisher :
- Nature Portfolio, 2018.
-
Abstract
- Given the recent Zika virus (ZIKV) epidemic, development of an effective vaccine is of high importance. Here, the authors use a licensed live-attenuated flavivirus vaccine backbone to develop a ZIKV vaccine and determine immunogenicity, safety and protection profiles in different animal models.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 9
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.788df413c3c54bebaab8d4b979a10833
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-018-02975-w