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An Overview of Indian Biomedical Research on the Chikungunya Virus with Particular Reference to Its Vaccine, an Unmet Medical Need

Authors :
Muhammed Muhsin Varikkodan
Faisal Kunnathodi
Sarfuddin Azmi
Tzong-Yuan Wu
Source :
Vaccines, Vol 11, Iss 6, p 1102 (2023)
Publication Year :
2023
Publisher :
MDPI AG, 2023.

Abstract

Chikungunya virus (CHIKV) is an infectious agent spread by mosquitos, that has engendered endemic or epidemic outbreaks of Chikungunya fever (CHIKF) in Africa, South-East Asia, America, and a few European countries. Like most tropical infections, CHIKV is frequently misdiagnosed, underreported, and underestimated; it primarily affects areas with limited resources, like developing nations. Due to its high transmission rate and lack of a preventive vaccine or effective treatments, this virus poses a serious threat to humanity. After a 32-year hiatus, CHIKV reemerged as the most significant epidemic ever reported, in India in 2006. Since then, CHIKV-related research was begun in India, and up to now, more than 800 peer-reviewed research papers have been published by Indian researchers and medical practitioners. This review gives an overview of the outbreak history and CHIKV-related research in India, to favor novel high-quality research works intending to promote effective treatment and preventive strategies, including vaccine development, against CHIKV infection.

Details

Language :
English
ISSN :
2076393X
Volume :
11
Issue :
6
Database :
Directory of Open Access Journals
Journal :
Vaccines
Publication Type :
Academic Journal
Accession number :
edsdoj.7827983cd45946389e20f8a8b8c861e9
Document Type :
article
Full Text :
https://doi.org/10.3390/vaccines11061102