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Plasma membrane phosphatidylinositol (4,5)-bisphosphate is critical for determination of epithelial characteristics

Authors :
Kaori Kanemaru
Makoto Shimozawa
Manabu Kitamata
Rikuto Furuishi
Hinako Kayano
Yui Sukawa
Yuuki Chiba
Takatsugu Fukuyama
Junya Hasegawa
Hiroki Nakanishi
Takuma Kishimoto
Kazuya Tsujita
Kazuma Tanaka
Toshiki Itoh
Junko Sasaki
Takehiko Sasaki
Kiyoko Fukami
Yoshikazu Nakamura
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Epithelial cells provide cell-cell adhesion to maintain the integrity of multicellular organisms. Here the authors show that phospholipid phosphatidylinositol (4,5)-bisphosphate is critical for the maintenance of epithelial characteristics.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.7823ce0d20e645f189c00d1084489ae8
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-30061-9