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Immune and spermatogenesis-related loci are involved in the development of extreme patterns of male infertility
- Source :
- Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
- Publication Year :
- 2022
- Publisher :
- Nature Portfolio, 2022.
-
Abstract
- A GWAS in a large case-control cohort of European ancestry identifies two genomic regions, the MHC class II gene HLA-DRB1 and an upstream locus of VRK1, that are associated with the most severe phenotype of spermatogenic failure.
- Subjects :
- Biology (General)
QH301-705.5
Subjects
Details
- Language :
- English
- ISSN :
- 23993642
- Volume :
- 5
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Communications Biology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.77b3fe3532a14229aef1e788bb1d7f9d
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s42003-022-04192-0