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Research progress on the role of N6-methyladenosine (m6A) RNA modification in reproductive system diseases

Authors :
ZHANG Yan, ZHU Meng-wen, LIU Tong, YANG Sheng, LIANG Ge-yu
Source :
Jichu yixue yu linchuang, Vol 41, Iss 9, Pp 1347-1351 (2021)
Publication Year :
2021
Publisher :
Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College., 2021.

Abstract

N6-methyladenosine (m6A) RNA modification is a post-transcriptional modification occurring on the 6th N atom of RNA adenine (A), regulating the structure, stability, splicing, output, translation and decay of mRNA, and thus extensively affecting the life processes of various organisms.This paper summarized the role and mechanism of various m6A methylase in the occurrence and development of reproductive system diseases and breast caner, in order to provide new basis for early diagnosis, treatment and improved prognosis of reproductive system diseases and breast caner.

Details

Language :
Chinese
ISSN :
10016325
Volume :
41
Issue :
9
Database :
Directory of Open Access Journals
Journal :
Jichu yixue yu linchuang
Publication Type :
Academic Journal
Accession number :
edsdoj.775cfab7dfc74e2e906582f28004c3e9
Document Type :
article