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Preparation of nanodiamond anchored on copper tannic acid as a heterogenous catalyst for synthesis of 1,4-benzodiazepines derivatives
- Source :
- Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
- Publication Year :
- 2024
- Publisher :
- Nature Portfolio, 2024.
-
Abstract
- Abstract In this research, a new and eco-friendly heterogeneous catalyst (ND@Tannicacid-Cu) was synthesized based on nanodiamond and copper tannic acid via esterification process. The as-prepared catalyst was characterized by Fourier transforms infrared spectroscopy (FT-IR), energy dispersive X-ray spectroscopy (EDX), scanning electron microscopy (SEM), and X-ray diffraction (XRD) methods. The catalytic efficacy of the intended catalyst was examined by one-step three-component reaction of 1,4-benzodiazepine derivatives from a mixture of ortho-phenylenediamine, aromatic aldehydes, and dimedone under mild conditions. In all instances, corresponding 2,4-benzodiazepines derivatives were synthesized with high efficiency, short reaction time, straightforward work up procedure, no requirement for column-chromatography, and cost-effective catalyst. The heterogeneous catalyst was easily recycled using fillers, and it can be reused for eight cycles without significantly diminishing its performance.
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 14
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Scientific Reports
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.77374b5c5b0a42dc98e75c1be8f49f8a
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41598-024-58563-0