Back to Search
Start Over
Conditions, pathogenesis, and progression of diabetic kidney disease and early decliner in Japan
- Source :
- BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)
- Publication Year :
- 2020
- Publisher :
- BMJ Publishing Group, 2020.
-
Abstract
- ObjectiveGlomerular filtration rate (GFR) decreases without or prior to the development of albuminuria in many patients with diabetes. Therefore, albuminuria and/or a low GFR in patients with diabetes is referred to as diabetic kidney disease (DKD). A certain proportion of patients with diabetes show a rapid progressive decline in renal function in a unidirectional manner and are termed early decliners. This study aimed to elucidate the prevalence of DKD and early decliners and clarify their risk factors.Research design and methodsThis combination cross-sectional and cohort study included 2385 patients with diabetes from 15 hospitals. We defined DKD as a urinary albumin to creatinine ratio (ACR) ≥30 mg/gCr and/or estimated glomerular filtration rate (eGFR)
- Subjects :
- Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Subjects
Details
- Language :
- English
- ISSN :
- 20524897
- Volume :
- 8
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- BMJ Open Diabetes Research & Care
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.76a91b308edc4e0dad54504006c63831
- Document Type :
- article
- Full Text :
- https://doi.org/10.1136/bmjdrc-2019-000902