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Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections

Authors :
Alan Bénard
Anne Jacobsen
Maximilian Brunner
Christian Krautz
Bettina Klösch
Izabela Swierzy
Elisabeth Naschberger
Malgorzata J. Podolska
Dina Kouhestani
Paul David
Torsten Birkholz
Ixchel Castellanos
Denis Trufa
Horia Sirbu
Marcel Vetter
Andreas E. Kremer
Kai Hildner
Andreas Hecker
Fabian Edinger
Matthias Tenbusch
Petra Mühl-Zürbes
Alexander Steinkasserer
Enrico Richter
Hendrik Streeck
Marc M. Berger
Thorsten Brenner
Markus A. Weigand
Filip K. Swirski
Georg Schett
Robert Grützmann
Georg F. Weber
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Here, the authors identify interleukin-3 as a predictive marker for severity and outcome of SARS-CoV-2 infection in a multi-center, prospective study and find that patients with severe COVID-19 have reduced circulating plasmacytoid dendritic cell levels compared to non-severe COVID-19 patients.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.75b62b7c584d48a9ba0f701d8cd0cf
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-21310-4