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Insight into the pharmacological effects of andrographolide in musculoskeletal disorders
- Source :
- Biomedicine & Pharmacotherapy, Vol 146, Iss , Pp 112583- (2022)
- Publication Year :
- 2022
- Publisher :
- Elsevier, 2022.
-
Abstract
- Andrographis paniculata (A. paniculata) is a traditional herbal medicine that has been widely used in Asian countries for hundreds of years. Andrographolide (AG) is a diterpene lactone extracted from A. paniculata. Owing to the in-depth study of pharmacological mechanisms, the therapeutic potential of AG, including its anti-inflammatory, anti-tumor, and immunoregulatory attributes, has attracted the attention of many researchers. Studies testing the therapeutic effects of AG have demonstrated desirable results in the treatment of a variety of clinical diseases. With high safety and various biological functions, AG might be a promising candidate for the treatment of musculoskeletal disorders. Here, we review all available literatures to summarize the pharmacological effects of AG and facilitate further researches on musculoskeletal diseases.
Details
- Language :
- English
- ISSN :
- 07533322
- Volume :
- 146
- Issue :
- 112583-
- Database :
- Directory of Open Access Journals
- Journal :
- Biomedicine & Pharmacotherapy
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.74c948e8d2b84099880655bcc190e9dd
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.biopha.2021.112583