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Whole-Genome Analysis of Mycobacterium tuberculosis from Patients with Tuberculous Spondylitis, Russia

Authors :
Ekaterina Chernyaeva
Mikhail Rotkevich
Ksenia Krasheninnikova
Andrey Yurchenko
Anna Vyazovaya
Igor Mokrousov
Natalia Solovieva
Viacheslav Zhuravlev
Piotr Yablonsky
Stephen J. O’Brien
Source :
Emerging Infectious Diseases, Vol 24, Iss 3, Pp 579-583 (2018)
Publication Year :
2018
Publisher :
Centers for Disease Control and Prevention, 2018.

Abstract

Whole-genome analysis of Mycobacterium tuberculosis isolates collected in Russia (N = 71) from patients with tuberculous spondylitis supports a detailed characterization of pathogen strain distributions and drug resistance phenotype, plus distinguished occurrence and association of known resistance mutations. We identify known and novel genome determinants related to bacterial virulence, pathogenicity, and drug resistance.

Details

Language :
English
ISSN :
10806040 and 10806059
Volume :
24
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Emerging Infectious Diseases
Publication Type :
Academic Journal
Accession number :
edsdoj.7467e68eb55d4d5b98b9a4d0f62bf3f2
Document Type :
article
Full Text :
https://doi.org/10.3201/eid2403.170151