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Oligonucleotide Labelling Using a Fluorogenic 'Click' Reaction with a Hemicarboxonium Salt
- Source :
- Molecules, Vol 18, Iss 10, Pp 12966-12976 (2013)
- Publication Year :
- 2013
- Publisher :
- MDPI AG, 2013.
-
Abstract
- Two fluorescent streptocyanine labelled oligonucleotides have been synthesized by a simple “click” reaction between a non-fluorescent hemicarboxonium salt and aminoalkyl functionalized thymidines within the oligonucleotide and their spectrophotometric properties have been studied.
- Subjects :
- nucleotides
modified analogues
diagnostic potentialities
Organic chemistry
QD241-441
Subjects
Details
- Language :
- English
- ISSN :
- 14203049
- Volume :
- 18
- Issue :
- 10
- Database :
- Directory of Open Access Journals
- Journal :
- Molecules
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.73f07bf9d1b4086aca0e7dbcb693a24
- Document Type :
- article
- Full Text :
- https://doi.org/10.3390/molecules181012966