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МATHEMATICAL MODELING OF ETHANOL AND LACTIC ACID BIOSYNTHESIS BY THERMOPHILIC Geobacillus BACTERIA

Authors :
M. A. Nuriddinov
F. V. Kazantsev
A. S. Rozanov
K. N. Kozlov
S. E. Peltek
I. R. Akberdin
N. A. Kolchanov
Source :
Вавиловский журнал генетики и селекции, Vol 17, Iss 4/1, Pp 686-704 (2015)
Publication Year :
2015
Publisher :
Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders, 2015.

Abstract

A mathematical model of the ethanol and lactic acid biosynthesis in the cells of Geobacillus spp. developed and adapted to the available experimental data is presented. It is shown that the mathematical model allows in silico design of genetic engineering experiments with the Geobacillus spp. bacterium and prediction of the dynamics of changes in synthesized ethanol and lactic acid concentrations depending on the molecular manipulations with the activity of enzymes of the metabolic system.

Details

Language :
English, Russian
ISSN :
25003259
Volume :
17
Issue :
4/1
Database :
Directory of Open Access Journals
Journal :
Вавиловский журнал генетики и селекции
Publication Type :
Academic Journal
Accession number :
edsdoj.7394515eb2745b48dc0c680fcb5f47d
Document Type :
article