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Early Experiences With COVID-19 Testing in Transplantation
- Source :
- Transplantation Direct, Vol 6, Iss 7, p e572 (2020)
- Publication Year :
- 2020
- Publisher :
- Wolters Kluwer, 2020.
-
Abstract
- Background. The early effects of coronavirus disease 2019 (COVID-19) on transplantation are dramatic: >75% of kidney and liver programs are either suspended or operating under major restrictions. To resume transplantation, it is important to understand the prevalence of COVID-19 among transplant recipients, donors, and healthcare workers (HCWs) and its associated mortality. Methods. To investigate this, we studied severe acute respiratory syndrome coronavirus 2 diagnostic test results among patients with end-stage renal disease or kidney transplants from the Johns Hopkins Health System (n = 235), and screening test results from deceased donors from the Southwest Transplant Alliance Organ Procurement Organization (n = 27), and donors, candidates, and HCWs from the National Kidney Registry and Viracor-Eurofins (n = 253) between February 23 and April 15, 2020. Results. We found low rates of COVID-19 among donors and HCWs (0%–1%) who were screened, higher rates of diagnostic tests among patients with end-stage renal disease or kidney transplant (17%–20%), and considerable mortality (7%–13%) among those who tested positive. Conclusions. These findings suggest the threat of COVID-19 for the transplant population is significant and ongoing data collection and reporting is critical to inform transplant practices during and after the pandemic.
Details
- Language :
- English
- ISSN :
- 23738731 and 00000000
- Volume :
- 6
- Issue :
- 7
- Database :
- Directory of Open Access Journals
- Journal :
- Transplantation Direct
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.72dd57ec71d741278be7a13572b666d8
- Document Type :
- article
- Full Text :
- https://doi.org/10.1097/TXD.0000000000001024