Collodion baby: A report of 4 cases

Introduction: The term collodion baby refers to a clinical entity noted in newborns who are enmeshed by a translucent, cornified substance like sheets of uniform texture so called (collodion membrane) which gives the whole body surface a varnished appearance. Although, some other diseases and conditions may lead to collodion membrane formation, in almost all the cases the cause is an autosomal recessive ichthyosiform disease. Case Presentation: The first three cases are all from a consanguineously married couple of Fulani decent. The abnormal appearances of the babies’ skin were all noticed at birth. Parents are first cousins. The last case is a female born at GA of 40wks through emergency caesarian section due to poor progress of labor. She was admitted into the Newborn with abnormal skin. These series are crucial so as to enable the pediatrician have a high index of suspicion of its existence and to be equipped with the skills to tackle the numerous complications that follow the disease. They contribute to mortality and morbidity among children in Nigeria and the exact etiology is unknown. However genetic and environmental factors among others are commonly implicated. This report is thus aimed at presenting these abnormalities which are rather rare and to highlight that early intervention improves the outcome in patients with these conditions. Conclusion: Early recognition of this clinical entity and early institution of appropriate therapy can definitely reduce morbidity and mortality in neonates.