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Ciprofloxacin induced toxic epidermal necrolysis with cholestatic hepatitis: A case report with literature review and revisit to the Naranjo adverse drug reaction probability scale

Authors :
Bishal Dhakal
Sagun Dawadi
Laxman Khadka
Sujan Bohara
Shashank Neupane
Priajan Ale Magar
Bishnu Deep Pathak
Binit Upadhaya Regmi
Source :
Clinical Case Reports, Vol 10, Iss 12, Pp n/a-n/a (2022)
Publication Year :
2022
Publisher :
Wiley, 2022.

Abstract

Abstract Ciprofloxacin, among the many Fluoroquinolones, has been widely used as a broad‐spectrum antibiotic due to its wide range of action and relatively safe adverse effect profile. However, among the cutaneous adverse drug reactions due to Ciprofloxacin, toxic epidermal necrolysis occurring along with cholestatic hepatitis is a rare one. Here, we present a case of a 22‐year‐old male patient who was diagnosed with toxic epidermal necrolysis with cholestatic hepatitis secondary to Ciprofloxacin. Naranjo adverse drug reaction probability scale was used for the causal association.

Details

Language :
English
ISSN :
20500904
Volume :
10
Issue :
12
Database :
Directory of Open Access Journals
Journal :
Clinical Case Reports
Publication Type :
Academic Journal
Accession number :
edsdoj.7241d8db815240a3a25f5472191a866b
Document Type :
article
Full Text :
https://doi.org/10.1002/ccr3.6766