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High seroprevalence and associated risk factors for hepatitis B virus infection among pregnant women living with HIV in Mtwara region, Tanzania
- Source :
- Bulletin of the National Research Centre, Vol 47, Iss 1, Pp 1-12 (2023)
- Publication Year :
- 2023
- Publisher :
- SpringerOpen, 2023.
-
Abstract
- Abstract Background Hepatitis B virus (HBV) infection continues to be a global public health problem. As of 2019, there were 296 million people chronically infected with HBV, resulting in nearly 1 million deaths from decompensated cirrhosis or hepatocellular carcinoma. The seroprevalence of HBV infection among pregnant women in Tanzania was reported to range between 3.8 and 8.03%. However, data on HBV infection in HIV-infected pregnant women is limited. We aimed to determine the seroprevalence and associated risk factors for HBV infection among HIV-infected pregnant women in selected health facilities in the Mtwara region. This was a health facility-based quantitative cross-sectional study conducted for three months (from February to April 2022). A structured questionnaire was used to collect information from the study participants. A total of 4 ml of blood was collected for HBV screening and confirmatory tests using rapid diagnostic tests and automated Enzyme-Linked Immunosorbent Assay (ELISA) tests, respectively. The logistic regression model was used to identify significant variables for HBV infection. Results Two hundred and twenty (n = 220) pregnant women living with HIV were enrolled in this study, with a median age of 32.7 years (Interquartile range (IQR) 27.6–37.6). The seroprevalence of HBV, chronic, and acute HBV infections were 10.5%, 10.0%, and 0.5%, respectively. We found that the multiparous women [aOR 11.99: 95% CI 1.11–129.01, p = 0.040], being infected with syphilis [aOR 27.65: 95% CI 9.07–84.30, p
Details
- Language :
- English
- ISSN :
- 25228307
- Volume :
- 47
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Bulletin of the National Research Centre
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.71e79c841c4fb3a8087566744bd305
- Document Type :
- article
- Full Text :
- https://doi.org/10.1186/s42269-023-01019-8