Evaluation of multi-dimensional intelligent management in improving compliance of subcutaneous specific immunotherapy in children

Objective To evaluate the effect of multi-dimensional intelligent management on improving the compliance of subcutaneous specific immunotherapy （SCIT） in children. Methods 162 children diagnosed with allergic rhinitis（AR）and（or） allergic asthma（AS） receiving SCIT were recruited in this study.85 children received routine management combined with multi-dimensional intelligent management were assigned into the intelligent group and 77 children received routine management were allocated into the control group. The SCIT shedding rate in the initial treatment stage and the time taken to reach the maintenance phase were compared between two groups. The clinical efficacy of SCIT in children was assessed by the symptom score for AR,AS symptom scores （daytime and nighttime）, visual analogue scale （VAS） score and medication score were compared between two groups. The improvement of the scores of each scale from the beginning of SCIT to the maintenance treatment was evaluated and compared between two groups. The degree of satisfaction was also statistically compared between two groups. Results There were significant differences in shedding rate during the initial treatment stage （0.0% vs. 7.8%, P < 0.01）, the time taken to reach the maintenance treatment stage （15（15, 16） weeks vs. 16 （15, 18） weeks, P < 0.01）between two groups. The symptom score for AR, AS symptom scores （daytime and nighttime）,VAS score, medication score and degree of satisfaction in the intelligent group were superior to those in the control group （all P < 0.01）. Conclusion Application of multi-dimensional intelligent management contributes to improving the compliance of SCIT, shortening the time taken to reach the maintenance phase, enhancing clinical efficacy and degree of satisfaction in children with airway allergic diseases.