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Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response
- Source :
- Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
- Publication Year :
- 2021
- Publisher :
- Nature Portfolio, 2021.
-
Abstract
- The heterogeneity of breast cancer has a major role in drug response and resistance. In this study, the authors use patient-derived tumour xenografts as a platform for drug testing and correlation with single-cell proteomic phenotypes characterized by mass cytometry.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723 and 06795129
- Volume :
- 12
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.70db0dc523da4d5ab06795129ce34559
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-021-22303-z