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Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases

Authors :
Haibing He
Guangkai Bian
Corey J. Herbst-Gervasoni
Takahiro Mori
Stephen A. Shinsky
Anwei Hou
Xin Mu
Minjian Huang
Shu Cheng
Zixin Deng
David W. Christianson
Ikuro Abe
Tiangang Liu
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Terpene cyclases catalyze the formation of diverse hydrocarbon scaffolds found in terpenoids. Here, the authors report the cryptic function of class I terpene cyclases as aromatic prenyltransferases and the universality of this cryptic feature is confirmed using enzymes from different sources.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.70d380b1bf6424697e7827e67324201
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-17642-2