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A nonlinear relapse model with disaggregated contact rates: Analysis of a forward-backward bifurcation

Authors :
Jimmy Calvo-Monge
Fabio Sanchez
Juan Gabriel Calvo
Dario Mena
Source :
Infectious Disease Modelling, Vol 8, Iss 3, Pp 769-782 (2023)
Publication Year :
2023
Publisher :
KeAi Communications Co., Ltd., 2023.

Abstract

Throughout the progress of epidemic scenarios, individuals in different health classes are expected to have different average daily contact behavior. This contact heterogeneity has been studied in recent adaptive models and allows us to capture the inherent differences across health statuses better. Diseases with reinfection bring out more complex scenarios and offer an important application to consider contact disaggregation. Therefore, we developed a nonlinear differential equation model to explore the dynamics of relapse phenomena and contact differences across health statuses. Our incidence rate function is formulated, taking inspiration from recent adaptive algorithms. It incorporates contact behavior for individuals in each health class. We use constant contact rates at each health status for our analytical results and prove conditions for different forward-backward bifurcation scenarios. The relationship between the different contact rates heavily influences these conditions. Numerical examples highlight the effect of temporarily recovered individuals and initial conditions on infected population persistence.

Details

Language :
English
ISSN :
24680427
Volume :
8
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Infectious Disease Modelling
Publication Type :
Academic Journal
Accession number :
edsdoj.70d1fa493c7242b0b124c0680faadfde
Document Type :
article
Full Text :
https://doi.org/10.1016/j.idm.2023.06.004