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Indeterminate cell histiocytosis successfully treated with phototherapy
- Source :
- Autopsy and Case Reports, Vol 6, Iss 2 (2016)
- Publication Year :
- 2016
- Publisher :
- University of São Paulo, 2016.
-
Abstract
- First described in 1985, intermediate cell histiocytosis is a rare disorder of the cutaneous dendritic cell group with a varied clinical presentation and evolution. The pathologic substrate is constituted by the proliferation of indeterminate cells (ICs) that are immunophenotypically characterized by the positivity of CD1a, CD68, and faint/focal S100, plus the negativity for CD207 (langerin). The authors present the case of a healthy elderly woman who presented generalized dome-shaped reddish cutaneous nodules over her trunk, neck, face, and extremities over a period of 18 months. A laboratory and imaging work-up ruled out internal involvement. The skin biopsy was consistent with IC histiocytosis. The patient was treated with narrowband ultraviolet B phototherapy, which resulted in an excellent short-term outcome
- Subjects :
- Histiocytosis
Skin Diseases
Phototherapy
Medicine
Internal medicine
RC31-1245
Subjects
Details
- Language :
- English
- ISSN :
- 22361960
- Volume :
- 6
- Issue :
- 2
- Database :
- Directory of Open Access Journals
- Journal :
- Autopsy and Case Reports
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.70bc058bd2f34703bec3ee7e607a29e5
- Document Type :
- article
- Full Text :
- https://doi.org/10.4322/acr.2016.038