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Linear stability for a free boundary problem modeling the growth of tumor cord with time delay
- Source :
- Mathematical Biosciences and Engineering, Vol 21, Iss 2, Pp 2344-2365 (2024)
- Publication Year :
- 2024
- Publisher :
- AIMS Press, 2024.
-
Abstract
- This paper was concerned with a free boundary problem modeling the growth of tumor cord with a time delay in cell proliferation, in which the cell location was incorporated, the domain was bounded in $ \mathbb{R}^2 $, and its boundary included two disjoint closed curves, one fixed and the other moving and a priori unknown. A parameter $ \mu $ represents the aggressiveness of the tumor. We proved that there exists a unique radially symmetric stationary solution for sufficiently small time delay, and this stationary solution is linearly stable under the nonradially symmetric perturbations for any $ \mu > 0 $. Moreover, adding the time delay in the model leads to a larger stationary tumor. If the tumor aggressiveness parameter is bigger, the time delay has a greater effect on the size of the stationary tumor, but it has no effect on the stability of the stationary solution.
Details
- Language :
- English
- ISSN :
- 15510018
- Volume :
- 21
- Issue :
- 2
- Database :
- Directory of Open Access Journals
- Journal :
- Mathematical Biosciences and Engineering
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.70996accd19f4f239e5bf8761d80a007
- Document Type :
- article
- Full Text :
- https://doi.org/10.3934/mbe.2024103?viewType=HTML