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Effect of surface grain boundary density on preosteoblast proliferation on titanium

Authors :
Terry C. Lowe
Rebecca A. Reiss
Patrick E. Illescas
Casey F. Davis
Melanie C. Connick
Johnny A. Sena
Source :
Materials Research Letters, Vol 8, Iss 6, Pp 239-246 (2020)
Publication Year :
2020
Publisher :
Taylor & Francis Group, 2020.

Abstract

Studies since 2004 have shown that the cytocompatibility of ultrafine grain (UG) commercial purity (CP) titanium exceeds that of coarse grain (CG) CP titanium (Ti) by 30% to 20-fold. To isolate the factors affecting this large reported variability of CP titanium’s cytocompatibility, discs of UG and CG titanium were fabricated with controlled texture and roughness. The discs were seeded with MC3T3-E1 pre-osteoblastic cells and cultured for 72 h. The proliferation of cells on polished UG-Ti exceeded unpolished CG-Ti 3.04-fold. Cell proliferation was found to correlate with a new biophysical parameter, the average grain boundary length per surface-attached cell.

Details

Language :
English
ISSN :
21663831
Volume :
8
Issue :
6
Database :
Directory of Open Access Journals
Journal :
Materials Research Letters
Publication Type :
Academic Journal
Accession number :
edsdoj.7087d7edd320429bba0b139a4b6db5eb
Document Type :
article
Full Text :
https://doi.org/10.1080/21663831.2020.1744758