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Associations of autozygosity with a broad range of human phenotypes
- Source :
- Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
- Publication Year :
- 2019
- Publisher :
- Nature Portfolio, 2019.
-
Abstract
- Inbreeding depression has been observed in many different species, but in humans a systematic analysis has been difficult so far. Here, analysing more than 1.3 million individuals, the authors show that a genomic inbreeding coefficient (FROH) is associated with disadvantageous outcomes in 32 out of 100 traits tested.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 10
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.701d2fda0b6343e98f5974339f0a8eb7
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-019-12283-6