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Dammarane-Type Triterpenoids from The Stembark of Aglaia argentea (Meliaceae)

Dammarane-Type Triterpenoids from The Stembark of Aglaia argentea (Meliaceae)

Authors :
Ace Tatang Hidayat
Kindi Farabi
Ida Nur Farida
Kansy Haikal
Nurlelasari Nurlelasari
Desi Harneti Putri Huspa
Rani Maharani
Unang Supratman
Yoshihito Shiono
Source :
Jurnal Kimia Valensi, Vol 4, Iss 1, Pp 7-13 (2018)
Publication Year :
2018
Publisher :
Syarif Hidayatullah Jakarta State Islamic University, 2018.

Abstract

Two dammarane-type triterpenoids, 20S,24S-epoxy-3α,25-dihydroxydammarane (1) and 3α-acetyl-20S,24S-epoxy-3α,25-dihydroxydammarane (2), have been isolated from the stembark of Aglaia argentea. The chemical structure of compounds (1 and 2) were identified by spectroscopic evidences including UV, IR, 1D-NMR, 2D-NMR and MS as well as by comparing with previously reported spectral data. Those compounds were isolated from this plant for first time. Compounds (1 and 2) showed cytotoxic activity against P-388 murine leukemia cells with IC50 values of 23.96 and 8.14 mM, respectively. DOI:http://dx.doi.org/10.15408/jkv.v4i1.7065

Subjects

Subjects :
Chemistry
QD1-999

Details

Language :
Indonesian
ISSN :
24606065 and 25483013
Volume :
4
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Jurnal Kimia Valensi
Publication Type :
Academic Journal
Accession number :
edsdoj.6f3a6024025a4de3be70c2d6dc371974
Document Type :
article
Full Text :
https://doi.org/10.15408/jkv.v4i1.7065