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Patient-Factors Influencing the 2-Year Trajectory of Mental and Physical Health in Prostate Cancer Patients

Authors :
Alessandro Cicchetti
Marianna Noale
Paola Dordoni
Barbara Noris Chiorda
Letizia De Luca
Lara Bellardita
Rodolfo Montironi
Filippo Bertoni
Pierfrancesco Bassi
Riccardo Schiavina
Mauro Gacci
Sergio Serni
Francesco Sessa
Marco Maruzzo
Stefania Maggi
Riccardo Valdagni
Source :
Current Oncology, Vol 29, Iss 11, Pp 8244-8260 (2022)
Publication Year :
2022
Publisher :
MDPI AG, 2022.

Abstract

This study aimed to examine the physical and mental Quality of Life (QoL) trajectories in prostate cancer (PCa) patients participating in the Pros-IT CNR study. QoL was assessed using the Physical (PCS) and Mental Component Score (MCS) of Short-Form Health Survey upon diagnosis and two years later. Growth mixture models were applied on 1158 patients and 3 trajectories over time were identified for MCS: 75% of patients had constantly high scores, 13% had permanently low scores and 12% starting with low scores had a recovery; the predictors that differentiated the trajectories were age, comorbidities, a family history of PCa, and the bowel, urinary and sexual functional scores at diagnosis. In the physical domain, 2 trajectories were defined: 85% of patients had constantly high scores, while 15% started with low scores and had a further slight decrease. Two years after diagnosis, the psychological and physical status was moderately compromised in more than 10% of PCa patients. For mental health, the trajectory analysis suggested that following the compromised patients at diagnosis until treatment could allow identification of those more vulnerable, for which a level 2 intervention with support from a non-oncology team supervised by a clinical psychologist could be of help.

Details

Language :
English
ISSN :
17187729 and 11980052
Volume :
29
Issue :
11
Database :
Directory of Open Access Journals
Journal :
Current Oncology
Publication Type :
Academic Journal
Accession number :
edsdoj.6ecf344b965344c9891b39f0a70fcb25
Document Type :
article
Full Text :
https://doi.org/10.3390/curroncol29110651