PROINFLAMMATORY CYTOKINES PROFILE IN WOMEN WITH GENITOURINARY TRICHOMONIASIS

Abstract. Study results of vaginal secretion cytokine system in 25 patients with urogenital trichomoniasis are presented. Concentration of interleukins:IL-1α, IL-1β, RAIL-1, TNFa, IL-8, IFN-γ has been performed. The character of pro-inflammatory cytokines changes in the local immunity system in females with urogenital trichomoniasis has been studied in comparison with these values in healthy females. It has been established that infected females have increased levels of IL-1α, IL-1β, RAIL-1, TNFα, IL-8, while IFN-γ concentration is decreased. The obtained results enable to get a deeper insight into the cytokine-mediated reactions in the local immunity system of genital tracts in case of trichomoniasis.